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M94A2248.TXT
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1994-10-25
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Document 2248
DOCN M94A2248
TI Monitoring incident HIV infections in Ontario. Ontario HIV Seroconverter
Study Group.
DT 9412
AU Galli R; Major C; Fearon M; Green L; Calzavara L; HIV Laboratory,
Ontario Ministry of Health, Canada.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):347 (abstract no. PC0619). Unique
Identifier : AIDSLINE ICA10/94370327
AB OBJECTIVE: To track incident cases of HIV infection in Ontario. METHODS:
All diagnostic HIV testing for the Province is performed by the Ministry
of Health. Demographic information and results are recorded in a
computer data base. Follow up tests for HIV negative individuals are
monitored for seroconversion (SC). In addition, the laboratory has an
algorithm designed to detect early HIV infection. RESULTS: Between 1985
and June 1993, 442 seroconversions were documented, representing 3.4% of
all newly diagnosed cases (3.3% of male cases; 4.2% of female cases).
Over time, SC represented an increasing proportion of newly diagnosed
cases (1.3%-1986; 4.9%-1993). In 1993, 0.6% of male and 0.03% of female
negative retesters seroconverted. Approximately, 15% of SCs were
detected during the initial stages of HIV antibody development, before
full western blot positivity. Males represented 88% of SC; 9% were
female and for 3% sex was not indicated. Risk information was provided
for 75% of cases; for males: 81% were exclusively gay, 4% bisexual and
9% were IDU's. For females: 52% acquired HIV through heterosexual
transmission and 40% were IDU's. 51% of males and 56% of females were in
the 25-34 age group. The greatest increase in SC over time was seen in
homosexual males aged 20-39. While SCs have been detected in every
health area in the province, the majority, (70%) were tested in
Metropolitan Toronto. CONCLUSIONS: HIV seroconverters represent the
leading edge of the HIV epidemic. Gay men between 25-34 seem to be
particularly at risk. Establishment of a cohort of recent seroconverters
is critical to determine the cause of these prevention failures.
DE Adult Algorithms AIDS Serodiagnosis/*STATISTICS & NUMER DATA Female
Homosexuality/STATISTICS & NUMER DATA Human HIV
Infections/*EPIDEMIOLOGY/PREVENTION & CONTROL/TRANSMISSION HIV
Seropositivity/EPIDEMIOLOGY/TRANSMISSION HIV Seroprevalence Male
Ontario/EPIDEMIOLOGY *Population Surveillance Risk Factors MEETING
ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).